碩士 / 國立中央大學 / 電機工程研究所 / 97 / Steady-state auditory evoked field (SSAEF) is a technique which utilizes magnetoencephalography (MEG) to measure the magneto-physiological responses evoked by repetitive auditory stimuli. SSAEFs have been widely used in clinical application and suggested as a clinical idex for diagnosing the function of auditory cortex in human brain. Nevertheless, the SSVEP is susceptible to be affected by task-irrelevant noise and may sometimes deteriorate the correctness in clinical diagnoses. Accordingly, this study aims to develop an empirical mode decomposition (EMD) – based technique to extract SSAEPs so that the signal-to-noise ratio (SNR) of SSAEP can be greatly improved. The efficacy of the proposed method has been applied to study clinical tinnitus patients.
The genesis of tinnitus is still unclear and lacks of a reliably objective procedure for diagnosis in clinics. Recent studies have shown the auditory evoked potential / field (AEP/AEF) in patients with tinnitus are deviant from normal subjects. These evidences imply the pathogenesis of tinnitus might be associated with the central auditory plasticity, i.e., the functional reorganization of the auditory cortex, rather than the dysfunction of peripheral auditory sensory networks. In this study, we apply the concurrent measurements of auditory steady-state fields (SSAEFs) to investigate the profound signal processing of the interhemispheric inhibition and binaural interaction. With the localization of auditory-related neural sources by applying electric current dipole (ECD), the proposed EMD-based method may be a powerful tool to shed light on studying the development of tinnitus.
| Identifer | oai:union.ndltd.org:TW/097NCU05442092 |
| Date | January 2009 |
| Creators | Tian-cheng Chiu, 邱天成 |
| Contributors | Po-Lei Lee, 李柏磊 |
| Source Sets | National Digital Library of Theses and Dissertations in Taiwan |
| Language | zh-TW |
| Detected Language | English |
| Type | 學位論文 ; thesis |
| Format | 60 |
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