碩士 / 嘉南藥理科技大學 / 化妝品科技研究所 / 94 / Abstract
The application of herb natural products as a component of the cosmetic products is a trend at present in the cosmetics industry. A traditional Chinese medicine (TCM), Morus alba has a long history to treat humans diseases, which were reported such as tonic for blood and yin, and treatment of vertigo, tinnitus, insomnia with palpitation, weak digestion, premature white hair, thirst, diabetes with heat, and diarrhea with blood deficient.
In our present study, formosan folk medicine–M. Australis was investigated its whitening effect via the anti-tyrosinase assay and radical scavenging. Moreover, the comparison on the HPLC profiles of the extracts of M. australis’ MADC、MADM、 MⅠM、MⅡM、MⅢM and MⅣM was included in our study. We further separated the plant of M. australis into different parts, as leaves, branch (young twigs), branch-bark, stem, stem-bark, and unripe fruits to explore their inhibitory effects toward tyrosinase in contrast to the whitening effect of the commercial TCM drug, Son-Pai-Pi, the root-bark of M. alba.
Our results indicated that the extracts of M. australis’ MADM showed the inhibitory ratio toward typrosinase up to 90%, whereas the extract of Son-Pai-Pi did not show inhibitory toward tyrosinase. As for radical scavenging, DPPH, TEAC methods were conducted. It shows that the minimum inhibition concentrations by MADM, MAⅠM, MAⅡM , and MAⅢM are (1) 31, 187, 249,77 μg /ml respectively for DPPH SC50, (2) MADM is 15.6 μg /ml for TEAC SC50.
Based on our results, the MADM extracts of M. australis could be regarded as a component of a cosmetic product with whitening function. However, more detailed studies on the bioactive components of these extracts are necessary.
| Identifer | oai:union.ndltd.org:TW/094CNUP5793009 |
| Date | January 2006 |
| Creators | Yi Chiao, 白宜巧 |
| Contributors | none, 陳榮秀 |
| Source Sets | National Digital Library of Theses and Dissertations in Taiwan |
| Language | zh-TW |
| Detected Language | English |
| Type | 學位論文 ; thesis |
| Format | 117 |
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