Sinteza i biološka ispitivanja novih derivata žučnih kiselina / Synthesis and biological evaluation of new bile acid derivatives

Description

<p>U disertaciji je ostvarena sineza amida i oksazolina žučnih kiselina, kao i njihovih alkil i alkilidenskih derivata polazeći od holne kiseline. Ipitano je pona&scaron;anje različitih okso derivata žučnih kiselina u uslovima Grignard-ove i Wittig-ove reakcije. Ispitana je biolo&scaron;ka aktivnost odabranih sintetizovanih jedinjenja</p> / <p>Synhesis of bile acid amide and oxazoline derivatives, and their alkyl and alkylidene derivatives was accomplished starting from cholic acid. Also, chemical behavior of different bile acid oxo derivatives in Grignard and Wittig reaction was investigated. Biological activity&nbsp; of selected synthesized compounds was evaluated.</p>

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1. https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija148300263737447.pdf?controlNumber=(BISIS)104087&fileName=148300263737447.pdf&id=7154&source=NDLTD&language=en
2. https://www.cris.uns.ac.rs/record.jsf?recordId=104087&source=NDLTD&language=en

Tags

Additional Fields

Identifer	oai:union.ndltd.org:uns.ac.rs/oai:CRISUNS:(BISIS)104087
Date	07 April 2017
Creators	Bjedov Srđan
Contributors	Sakač Marija, Čanadi Janoš, Popsavin Mirjana, Markov Siniša, Poša Mihalj
Publisher	Univerzitet u Novom Sadu, Prirodno-matematički fakultet u Novom Sadu, University of Novi Sad, Faculty of Sciences at Novi Sad
Source Sets	University of Novi Sad
Language	Serbian
Detected Language	English
Type	PhD thesis