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The interaction between Apnea and Hypopnea Index and Heart Rate Variability

In recent years, sleep medicine has attracted many interests. Among many sleep disorder problems, the sleep apnea syndrome is of great importance. One of its side effects is its negative influences on cardiovascular system whose function can be monitored by ECG.
The regulation of the heart rate is extremely important for human body. In general, the heart rate variability is controlled by the balance of the sympathetic and the parasympathetic systems whose functions can be influenced by sleep apnea.
This work tries to establish the relation between the heart rate variability and AHI (Apnea & hypopnea index). Through the statistical methods, we analyze how the sleep apnea influences the low frequency (LF) and high frequency components of the RR intervals. With BMI, age and AHI as the independent variables, we set up the regression model to predict LF/HF
Our results demonstrate that, for men, the linear relationship between the LF/HF and AHI is statistically significant when AHI is higher than 45. This results may shed some light on developing HRV based diagnosis method for sleep apnea.

Identiferoai:union.ndltd.org:NSYSU/oai:NSYSU:etd-0711111-170713
Date11 July 2011
CreatorsChiang, Chen-Feng
ContributorsLiang-Wen Hang, Jiann-Der Lee, Chen-Wen Yen
PublisherNSYSU
Source SetsNSYSU Electronic Thesis and Dissertation Archive
LanguageCholon
Detected LanguageEnglish
Typetext
Formatapplication/pdf
Sourcehttp://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0711111-170713
Rightswithheld, Copyright information available at source archive

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