This thesis describes the development of a small molecule sensor for the detection of specific protein-protein interactions. The responsive sensor has been designed to produce a measurable signal upon a bivalent interaction with a dimeric protein target, and has the potential to probe the biological significance of specific binding events.
Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:505063 |
Date | January 2009 |
Creators | White, Rebecca |
Publisher | University of Leeds |
Source Sets | Ethos UK |
Detected Language | English |
Type | Electronic Thesis or Dissertation |
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