Magister Scientiae - MSc / Retinoblastoma binding prot
ein 6 (RBBP6) is a 250 kDa human splicing-associated
protein that is also known to
interact with tumour suppresso
r proteins p53 and pRb and to
mediate ubiquitination of p53 via its intera
ction with Hdm2. RBBP6 is highly up
regulated in oesophageal cancer, and has been shown to be a promising target for immunotherapy against the disease. RBBP6 is also known to play a role in mRNA splicing, cell cycle control and apoptosis. / South Africa
| Identifer | oai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:uwc/oai:etd.uwc.ac.za:11394/2833 |
| Date | January 2007 |
| Creators | Mulaudzi, Takalani |
| Contributors | Pugh, David J.R., Magister Scientiae - MSc, Faculty of Science |
| Publisher | University of the Western Cape |
| Source Sets | South African National ETD Portal |
| Language | English |
| Detected Language | English |
| Type | Thesis |
| Rights | University of the Western Cape |
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