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Efeitos do tratamento com Hidrogel na cicatriza??o de ?lceras venosas de membros inferiores: revis?o sistem?tica

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Previous issue date: 2014-02-04 / Chronic venous disease (CVD) is evident among the chronic diseases and
affects the elderly population and primarily is responsible for leg ulcers in this
population. The use of dressings in the care of a venous ulcer is a fundamental part
of the treatment for healing, however, evidence to assist in choosing the best
dressing is scarce. The main objective of this study was to evaluate the effectiveness
of treatment with hydrogel in the healing of venous ulcers using search methods,
synthesis of information and statistical research through a systematic review and
meta-analysis. Randomized controlled trials were selected in the following
databases: CENTRAL; DARE; NHS EED; MEDLINE; EMBASE; CINAHL. Beyond
these databases three websites were consulted to identify ongoing studies:
ClinicalTrials.gov, OMS ICTRP e ISRCTN. The primary outcomes were analyzed:
complete wound healing, incidence of wound infection and the secondary were:
changes in ulcer size, time to ulcer healing, recurrence of ulcer, quality of life of
participants, pain and costs of treatment. Four studies are currently included in the
review with a total of 250 participants. The use of hydrogel appears to be superior to
conventional dressing, gauze soaked in saline, for the healing of venous leg ulcers;
16/30 patients showed complete healing of ulcers (RR 5,33, 95%CI [1,73,16,42]).
The alginate gel was shown to be more effective when compared to the hydrogel
dressing in reduction of the wound area; 61,2% (? 26,2%) with alginate e 19,4% (?
24,3%) with hydrogel at the end of four weeks of treatment. Manuka honey has
shown to be similar to the hydrogel dressings in percentage of area reduction. This
review demonstrated that there is no evidence available about the effectiveness of
the hydrogel compared to other types of dressings on the healing of venous leg
ulcers of the lower limbs, thus demonstrating the need of future studies to assist
health professionals in choosing the correct dressing. / A doen?a venosa cr?nica (DVC) evidencia-se entre as doen?as cr?nicas por
acometer a popula??o idosa e ser a principal respons?vel pelas ?lceras de membros
inferiores nesta popula??o. O uso de adesivos no cuidado de uma ?lcera venosa ?
parte fundamental no tratamento para a cicatriza??o, no entanto, as evid?ncias para
auxiliar na escolha do melhor adesivo s?o escassas. O objetivo principal do estudo
foi avaliar a efic?cia do tratamento com o hidrogel na cicatriza??o de ?lceras
venosas mediante m?todos de busca, s?ntese de informa??o e an?lise estat?stica
atrav?s de uma revis?o sistem?tica com meta-an?lise. Foram selecionados estudos
controlados randomizados nas seguintes bases de dados: CENTRAL; DARE; NHS
EED; MEDLINE; EMBASE; CINAHL. Al?m dessas bases foram consultados tr?s
websites para identificar estudos em andamento: ClinicalTrials.gov, OMS ICTRP e
ISRCTN. Os desfechos prim?rios analisados foram: cicatriza??o completa das
?lceras e incid?ncia de infec??o das ?lceras e os secund?rios foram: altera??es no
tamanho da ?lcera, tempo de cicatriza??o das ?lceras, recorr?ncia das ?lceras,
qualidade de vida dos participantes, dor e custos do tratamento. Quatro estudos
est?o atualmente inclu?dos na revis?o com um total de 250 pacientes. O uso do
hidrogel parece ser superior ao curativo convencional, gaze embebida em salina,
para a cicatriza??o de ?lceras venosas de membros inferiores; 16/30 pacientes
apresentaram cicatriza??o completa das ?lceras (RR 5,33, 95%CI [1,73,16,42]). O
gel de alginato demonstrou ser mais efetivo quando comparado ao hidrogel quanto ?
redu??o da ?rea da ?lcera; 61,2% (? 26,2%) com o alginato e 19,4% (? 24,3%) com
o hidrogel ao final das quatro semanas de tratamento. O mel de Manuka demonstrou
ser similar ao hidrogel em rela??o ? porcentagem de redu??o da ?rea. Esta revis?o
mostrou que n?o existem evid?ncias dispon?veis a respeito da efic?cia do hidrogel
em rela??o aos outros tipos de curativo na cicatriza??o de ?lceras venosas de
membros inferiores, demonstrando assim a necessidade de futuras pesquisas para
auxiliar os profissionais da sa?de na escolha do adesivo correto

Identiferoai:union.ndltd.org:IBICT/oai:repositorio.ufrn.br:123456789/16749
Date04 February 2014
CreatorsRibeiro, Cibele Teresinha Dias
ContributorsCPF:02357307935, http://lattes.cnpq.br/2201375154363914, Oliveira, Andrea Lemos Bezerra de, CPF:88366685420, http://lattes.cnpq.br/2714513843188755, Bruno, Selma Sousa, CPF:44456042400, http://lattes.cnpq.br/4056770607573210, Fregonezi, Guilherme Augusto de Freitas
PublisherUniversidade Federal do Rio Grande do Norte, Programa de P?s-Gradua??o em Fisioterapia, UFRN, BR, Movimento e Sa?de
Source SetsIBICT Brazilian ETDs
LanguagePortuguese
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis
Formatapplication/pdf
Sourcereponame:Repositório Institucional da UFRN, instname:Universidade Federal do Rio Grande do Norte, instacron:UFRN
Rightsinfo:eu-repo/semantics/openAccess

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