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Pattern recognition lectins in normal and abnormal pregnancy.

Lui, Wai Ting. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2008. / Includes bibliographical references (leaves 96-106). / Abstracts in English and Chinese. / Abstract --- p.i / Acknowledgements --- p.v / Table of Content --- p.vii / List of Tables --- p.x / List of Figures --- p.xi / Publications --- p.xiii / Chapter Chapter 1 --- Innate Immunity --- p.1 / Chapter 1.1 --- Immunity --- p.1 / Chapter 1.1.1 --- Surface Barriers --- p.2 / Chapter 1.1.2 --- Cell-mediated Innate Immunity --- p.2 / Chapter 1.1.3 --- Humoral Innate Immunity --- p.3 / Chapter 1.2 --- Complement System --- p.4 / Chapter 1.2.1 --- The Classical Pathway --- p.5 / Chapter 1.2.2 --- The Alternative Pathway --- p.6 / Chapter 1.2.3 --- The lectin pathway --- p.7 / Chapter 1.3 --- Lectins --- p.8 / Chapter 1.3.1 --- Mannose binding lectin --- p.11 / Chapter 1.3.2 --- Ficolin --- p.11 / Chapter 1.3.2.1 --- L-ficolin --- p.12 / Chapter 1.3.2.2 --- H-ficolin --- p.12 / Chapter 1.3.2.3 --- M-ficolin --- p.13 / Chapter Chapter 2 --- Innate Immunity in Pregnancy --- p.15 / Chapter 2.1 --- Immune challenge --- p.15 / Chapter 2.2 --- Natural Antimicrobials --- p.15 / Chapter 2.3 --- Cell-mediated Immunity --- p.16 / Chapter 2.4 --- Humoral Immunity --- p.18 / Chapter Chapter 3 --- Current Study --- p.20 / Chapter 3.1 --- Aim and Objectives --- p.20 / Chapter 3.2 --- General Methodology --- p.21 / Chapter Chapter 4 --- Pattern recognition lectins in maternal liver and lung --- p.23 / Chapter 4.1 --- Introduction --- p.23 / Chapter 4.2 --- Materials and Methods --- p.23 / Chapter 4.2.1 --- Animals --- p.23 / Chapter 4.2.2 --- Protein extraction --- p.27 / Chapter 4.2.3 --- Antibodies --- p.27 / Chapter 4.2.4 --- Western Blot --- p.28 / Chapter 4.2.5 --- Immunohistochemistry --- p.29 / Chapter 4.3 --- Results --- p.31 / Chapter 4.3.1 --- Temporal expression of lectins in maternal liver in mice --- p.31 / Chapter 4.3.2 --- Temporal expression of lectins in maternal lung in mice --- p.31 / Chapter 4.3.3 --- Spatial expression of lectins in maternal liver in mice --- p.34 / Chapter 4.3.4 --- Spatial expression of lectins in maternal lung in mice --- p.37 / Chapter 4.4 --- Discussion --- p.39 / Chapter 4.5 --- Conclusion --- p.40 / Chapter Chapter 5 --- Pattern recognition lectins in endometrium --- p.42 / Chapter 5.1 --- Introduction --- p.42 / Chapter 5.2 --- Materials and Methods --- p.43 / Chapter 5.2.1 --- Animals --- p.43 / Chapter 5.2.2 --- Immunohistochemistry --- p.45 / Chapter 5.3 --- Results --- p.45 / Chapter 5.4 --- Discussion --- p.48 / Chapter 5.5 --- Conclusion --- p.50 / Chapter Chapter 6 --- Pattern recognition lectins in maternal-fetal interface --- p.51 / Chapter 6.1 --- Introduction --- p.51 / Chapter 6.2 --- Materials and Methods --- p.52 / Chapter 6.2.1 --- Animals --- p.52 / Chapter 6.2.2 --- Immunohistochemistry --- p.55 / Chapter 6.3 --- Results --- p.55 / Chapter 6.4 --- Discussion --- p.58 / Chapter 6.5 --- Conclusion --- p.59 / Chapter Chapter 7 --- Pattern recognition lectins in preeclampsia --- p.60 / Chapter 7.1 --- Introduction --- p.60 / Chapter 7.2 --- Materials and Methods --- p.62 / Chapter 7.2.1 --- Patients --- p.62 / Chapter 7.2.2 --- Protein extraction --- p.63 / Chapter 7.2.3 --- Western Blot --- p.63 / Chapter 7.2.4 --- Lectin immunohistochemistry --- p.64 / Chapter 7.2.5 --- Apoptosis immunohistochemistry --- p.65 / Chapter 7.3 --- Results --- p.66 / Chapter 7.3.1 --- Expression levels of ficolins in normal and preeclamptic placenta --- p.67 / Chapter 7.3.2 --- Spatial expression of ficolins in normal and preeclamptic placenta --- p.68 / Chapter 7.3.3 --- Co-localization of Fas and ficolins in preeclamptic placenta --- p.69 / Chapter 7.4 --- Discussion --- p.71 / Chapter 7.5 --- Conclusion --- p.75 / Chapter Chapter 8 --- Pattern recognition lectins in miscarriage --- p.76 / Chapter 8.1 --- Introduction --- p.76 / Chapter 8.2 --- Materials and Methods --- p.77 / Chapter 8.2.1 --- Patients --- p.77 / Chapter 8.2.2 --- Immunohistochemistry --- p.78 / Chapter 8.3 --- Results --- p.79 / Chapter 8.3.1 --- Spatial expression of lectins in normal placenta and placenta from miscarriage patients --- p.80 / Chapter 8.3.2 --- Spatial expression of lectins in normal decidua and decidua from miscarriage patients --- p.86 / Chapter 8.4 --- Discussion --- p.92 / Chapter 8.5 --- Conclusion --- p.93 / Chapter Chapter 9 --- Future plan --- p.94 / References --- p.96

Identiferoai:union.ndltd.org:cuhk.edu.hk/oai:cuhk-dr:cuhk_326456
Date January 2008
ContributorsLui, Wai Ting., Chinese University of Hong Kong Graduate School. Division of Obstetrics and Gynaecology.
Source SetsThe Chinese University of Hong Kong
LanguageEnglish, Chinese
Detected LanguageEnglish
TypeText, bibliography
Formatprint, xiii, 106 leaves : ill. ; 30 cm.
RightsUse of this resource is governed by the terms and conditions of the Creative Commons “Attribution-NonCommercial-NoDerivatives 4.0 International” License (http://creativecommons.org/licenses/by-nc-nd/4.0/)

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