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Drug delivery problems to TB patients in Gauteng

After declining for many years, the incidence of tuberculosis (TB) is on the increase
again. With TB resurgence there is also resistance of some TB strains to the commonly
used TB drugs. This condition is kno wn as multi-drug resistance tuberculosis (MDR TB).
Among all factors that increase TB and MDR TB, treatment compliance and completion
is the greatest challenge. MDR TB is mainly caused by poor adherence to TB treatment
by either the patient or the prescriber.
In order to improve patient adherence to treatment. Directly Observed Therapy (DOT)
has been implemented in many countries including South Africa. DOT means that each
consumption of TB drugs by the patient is observed by a reliable person. Even with DOT
in place, many patients still do not adhere to the prescribed treatment.
This study aimed at determining from health workers the following:
• Problems experienced by the health workers when giving treatment to TB patients,
• causes for non-adherence to TB treatment, and
• what could be done to make DOT more effective.
A questionnaire was used to gather information. Ail clinics rendering TB services in
Gauteng were considered in this study. Two questionnaires were sent to each of
the 138 participating clinics and had to be completed by any two health workers involved
in the treatment of TB patients. Only 69 of the 276 questionnaires sent, were returned
completed (25%).
Information gathered from the questionnaires revealed that patients seen at TB clinics in
Gauteng came from various residential areas including townships, suburban rural and
informal settlement. The Pearson chi squared test showed that there was no association
between the percentage of patients who completed treatment and the number of patients
seen at a clinic, or between the percentage of patients who completed treatment and the
working hours at a particular clinic.
The main cause of non-compliance shown by the results of this study was that patients
discontinued treatment as soon as they felt better. Other causes of non-compliance
mentioned by health workers included patient denial of having TB, ignorance, long
treatment periods and many drugs that were to be taken during treatment. Health workers
revealed that the main problem experienced in giving treatment to TB patients was that of
deiaulting. The majority of these respondents suggested education as one way of making
DOT more effective.
In terms o f this study, it can be concluded that education on TB at various levels namely
the patient, the health care worker and the community, is recommended. Education on the
disease TB and its optimal treatment will improve patient compliance, decrease
defaulting in delivering TB drugs to patients and make DOT more effective.

Identiferoai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:wits/oai:wiredspace.wits.ac.za:10539/14681
Date20 May 2014
CreatorsMabena, Confidence
Source SetsSouth African National ETD Portal
LanguageEnglish
Detected LanguageEnglish
TypeThesis
Formatapplication/pdf

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