Previous research has shown increased saccade latencies in patients with Alzheimer’s disease and mild cognitive impairment; however, this is not well-understood in patients with delirium. The present study investigates eye-tracking metrics to evaluate the feasibility of using eye-tracking to discern delirious patients from disease control patients. We recruited 24 participants from the inpatient and intensive care units (ICU) at Massachusetts General Hospital (MGH) and assessed for delirium via CAM-S, a screening tool for delirium. Participants were instructed to follow a dot stimulus as it moves across the laptop screen as their eye movements were simultaneously tracked by a Tobii Pro Fusion eye-tracker. Our experimental paradigm involved gap saccades (central fixation extinguishes before the centrifugal target appears), overlap saccades (central fixation remains after centrifugal target onset), horizontal smooth pursuit, and circular smooth pursuit tasks. The eye-tracking metrics discussed in this study are the calibration and validation accuracies, saccade latencies and total target gaze duration. Our eye-tracking method was able to capture subjects’ gaze direction and path, but further research is needed to draw strong conclusions about the feasibility to detect oculomotor abnormalities in patients with delirium.
| Identifer | oai:union.ndltd.org:bu.edu/oai:open.bu.edu:2144/43343 |
| Date | 10 November 2021 |
| Creators | Ching, Winnie |
| Contributors | Gupta, Anoopum |
| Source Sets | Boston University |
| Language | en_US |
| Detected Language | English |
| Type | Thesis/Dissertation |
| Rights | Attribution 4.0 International, http://creativecommons.org/licenses/by/4.0/ |
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