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The protective effects of the antioxidant combination of ferulic acid with vitamins C and E against UV-induced photodamage in human skin cells

Includes abstract. / Includes bibliographical references (leaves 91-122). / This study assessed the ability of 0.8 mM ferulic acid (FA), in combination with vitamins C and E, to reduce the effect of UVA-induced photodamage in human epidermal (HaCaTs) and dermal skin cells (primary human fibroblasts (HFbs) and murine 3T3 cells). Pretreatment with the FA and vitamins C and E (vEC) combination solution reduced UVAinduced ROS in human fibroblasts while pre-treatment with vEC individually led to a reduction in HaCaTs.

Identiferoai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:uct/oai:localhost:11427/12167
Date January 2010
CreatorsBone, Emma Lewis
ContributorsDavids, Lester
PublisherUniversity of Cape Town, Faculty of Health Sciences, Department of Medicine
Source SetsSouth African National ETD Portal
LanguageEnglish
Detected LanguageEnglish
TypeMaster Thesis, Masters, MSc
Formatapplication/pdf

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