Detection of Single-Molecule Optical Absorption at Room Temperature and Mechanistic Study of Transcriptional Bursting

Description

Advances in optical imaging techniques have allowed quantitative studies of many biological systems. This dissertation elaborates on our efforts in both developing novel imaging modalities based on detection of optical absorption and applying high-sensitivity fluorescence microscopy to the study of biology. / Chemistry and Chemical Biology

Links & Downloads

1. Chong, Shasha. 2014. Detection of Single-Molecule Optical Absorption at Room Temperature and Mechanistic Study of Transcriptional Bursting. Doctoral dissertation, Harvard University.
2. http://dissertations.umi.com/gsas.harvard:11501
3. http://nrs.harvard.edu/urn-3:HUL.InstRepos:12274110

Tags

Chemistry

DNA supercoiling

gyrase

optical absorption

single-molecule

transcriptional bursting

Additional Fields

Identifer	oai:union.ndltd.org:harvard.edu/oai:dash.harvard.edu:1/12274110
Date	06 June 2014
Creators	Chong, Shasha
Contributors	Xie, Xiaoliang Sunney
Publisher	Harvard University
Source Sets	Harvard University
Language	en_US
Detected Language	English
Type	Thesis or Dissertation
Rights	open