This thesis presents the results of three studies examining the management
of migraine in children. First we conducted a systematic review of all clinical
trials conducted in children and adolescents of the acute migraine therapy. A
meta-analysis of the 26 randomized controlled trials is presented. A single trial with a focus on Emergency Department (ED) management was identified. As such, we then examined current ED practice in two retrospective practice
variation studies. The first compared four regional hospital EDs where practice patterns were significantly different between mixed population EDs (both adult and pediatric patients) and the tertiary pediatric ED. The second examined practice variation among ten tertiary pediatric EDs in Canada where significant differences were again observed. Factors that influenced the choice of medications included increasing patient age and the physicians diagnosis of migraine. Important areas of future investigation include: (1) the effectiveness of intravenous fluids alone; and (2) the use of combined medications. / Clinical Epidemiology
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:AEU.10048/763 |
| Date | 11 1900 |
| Creators | Richer, Lawrence |
| Contributors | Rowe, Brian (Emergency Medicine), Sevcik, Bill (Emergency Medicine), Klassen, Terry (Pediatrics), Spady, Don (Pediatrics) |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Thesis |
| Format | 2511095 bytes, application/pdf |
| Relation | http://www.ncbi.nlm.nih.gov.login.ezproxy.library.ualberta.ca/pubmed/17501852?ordinalpos=20&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum |
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