£\1-antitrypsin¡]£\1-AT¡^is one of over 40-member family of serine protease inhibitors, regulating trypsin and elstase activities by the formation of covalently bound complex. The mechanism of which serpin and enzyme form covalent complex is not clear, but two theorise have been proposed. One is opposite pole theory (OPT) proposed by Huntington et al.¡]2000¡^, suggesting that after serpin is cleaved by serine protease, the P1-linked enzyme is over-swinging about 70
| Identifer | oai:union.ndltd.org:NSYSU/oai:NSYSU:etd-0725105-230130 |
| Date | 25 July 2005 |
| Creators | Ding, Shih-Shiou |
| Contributors | Ching-Mei Hsu, Hsin-Chih Lai, Shiping He |
| Publisher | NSYSU |
| Source Sets | NSYSU Electronic Thesis and Dissertation Archive |
| Language | Cholon |
| Detected Language | English |
| Type | text |
| Format | application/pdf |
| Source | http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0725105-230130 |
| Rights | unrestricted, Copyright information available at source archive |
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