An experimental and computational study on the epimeric contribution to the infrared spectrum of budesonide

Description

No / Budesonide is a mixture of 22R and 22S epimers. The epimeric content of budesonide was reported in both British and European pharmacopoeias to be within the range of 60-49/40-51 for R and S epimers, respectively. In this work, contribution of the two epimers to the overall infrared spectrum of budesonide has been investigated by quantum chemical calculations.

Links & Downloads

1. Ali, H.R.H., Edwards, H.G.M., Kendrick, J., Munshi, T. and Scowen, I.J. (2010). An experimental and computational study on the epimeric contribution to the infrared spectrum of budesonide. Drug Testing and Analysis. Vol. 2, No. 9, pp. 447¿451.
2. http://hdl.handle.net/10454/4620
3. https://doi.org/10.1002/dta.152

Tags

Budesonide

Epimers

Infrared

Pharmaceuticals

Quantum mechanics

Quantum chemical calculations

Additional Fields

Identifer	oai:union.ndltd.org:BRADFORD/oai:bradscholars.brad.ac.uk:10454/4620
Date	January 2010
Creators	Ali, H.R.H., Edwards, Howell G.M., Kendrick, John, Munshi, Tasnim, Scowen, Ian J.
Source Sets	Bradford Scholars
Language	English
Detected Language	English
Type	Article, No full-text in the repository