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Synthetic Study toward 3-(5, 6, 7, 8-Tetrahydro-[1, 8]naphthyridin-2-yl)propionaldehyde

The starting material 3-sulfonyl-5-methoxy glutarimide
was easily prepared via stepwise [3+3] annulation
of N-benzyl R-sulfonylacetamide with unsaturated
ester as we previously described.
We wish we could build tetrahtdronaphthridine skeleton via
stretching C-chain, modifying funtional group and RCM, then
complete the synthesis of key intermediate of small molecule
similar to RGD.

Identiferoai:union.ndltd.org:NSYSU/oai:NSYSU:etd-0719106-132105
Date19 July 2006
CreatorsHong, Bei-Tao
ContributorsNein-Chen Chang, Chin-Hsing, Chou, Meng-Yang, Chang, Cherng-Chyi, Tzeng
PublisherNSYSU
Source SetsNSYSU Electronic Thesis and Dissertation Archive
LanguageCholon
Detected LanguageEnglish
Typetext
Formatapplication/pdf
Sourcehttp://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0719106-132105
Rightsnot_available, Copyright information available at source archive

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