TfOH-catalyzed reaction of bispropargyl alcohols with 1,3-dicarbonyl compounds

Description

No / A transition-metal-free efficient method for the preparation of 1,2,3-trisubstituted benzenes from bispropargyl alcohols and 1,3-dicarbonyl compounds has been developed. The reaction of bispropargyl alcohol with 1,3-dicarbonyl compound proceeds through [3,3]-rearrangement, 6π-electrocyclization, and unexpected Csp3−Csp2 regioselective σ-bond cleavage processes.

Links & Downloads

1. Teng Q, Mo S, Pan J et al (2016) TfOH-catalyzed reaction of bispropargyl alcohols with 1,3-dicarbonyl compounds. Synthesis. 48(3): 455-461.
2. http://hdl.handle.net/10454/17870
3. https://doi.org/10.1055/s-0035-1560372

Tags

Bispropargyl alcohols

1

3-dicarbonyl compounds

[3

3]-rearrangement

C−C α′-moiety cleavage

6π-electrocyclization process

1

2

3-trisubstituted benzenes

Additional Fields

Identifer	oai:union.ndltd.org:BRADFORD/oai:bradscholars.brad.ac.uk:10454/17870
Date	03 June 2020
Source Sets	Bradford Scholars
Language	English
Detected Language	English
Type	Article, No full-text in the repository