The work herein comprises two distinct projects: the first involves the construction of allylic ketones and enones directly from primary alcohols, using a novel one-pot procedure. Following development of this methodology, its application to the synthesis of indolizidine alkaloid elaeokanidine A was investigated. The second research area concerns the development of a copper(II)-catalysed radical cyclisation reaction to form spirocyclic oxindoles directly from linear anilides, along with subsequent preliminary studies towards to the synthesis of spirotryprostatin A.
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:556111 |
| Date | January 2012 |
| Creators | Moody, Catherine Laura |
| Contributors | Taylor, Richard J. K. |
| Publisher | University of York |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Source | http://etheses.whiterose.ac.uk/2409/ |
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