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A novel linker and its application for carbohydrate chemistry on the solid phase

The novel <i>exo</i>-enzyme cleavable linker <i>N</i>-1-(4-(3-aminopropylcarbamoyl)-phenyl)ethylsulfanyl)-methyl)-1-phenylacetamide (1) was successfully synthesised and its potential for use in solid phase carbohydrate chemistry was investigated. Sugar substrates were synthesised in solution and attached to solid support <i>via exo</i>-linker 1, which is also cleavable under mildly acidic conditions. (Fig. 9963)

Identiferoai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:642231
Date January 2000
CreatorsBurgess, Ian David
PublisherUniversity of Edinburgh
Source SetsEthos UK
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation
Sourcehttp://hdl.handle.net/1842/13266

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