The use of short high voltage pulses to overcome the barrier of the cell membrane by creating pores is known as electroporation. Pulsed electric fields can cause irreversible and reversible breakdown of the cell membrane thereby this technology can be applicable for sterilization processes as well as to enhance the transportation rate of foreign particles across the membrane. Transformation efficiency still remains the challenging aspect of the process. Due to the limitations of the pulse generators; available, the past research on electroporation has been limited to small treatment volumes with limited flexibility to optimise the process parameters.
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:502335 |
| Date | January 2008 |
| Creators | Avulamanda, Chandan |
| Publisher | University of Strathclyde |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
Page generated in 0.0244 seconds