The molecular machinery responsible for the generation of transport carriers that move cargo from the Golgi complex to the plasma membrane relies on a tight physical and functional interplay between proteins and lipids. Among the lipid-binding proteins composing this machinery, we previously identified the four-phosphate adaptor proteins FAPP1 and FAPP2 (FAPPs), the pleckstrin homology domain of which binds phosphatidylinositol 4-phosphate and the small GTPase ARFl.
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:489914 |
| Date | January 2008 |
| Creators | D'Angelo, Giovanni |
| Publisher | Open University |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
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