Polyketides are a class of secondary metabolites that includes compounds with antibiotic and anticancer properties. In type I polyketide synthesis, the individual activities are arranged into large | polyproteins, while in type II polyketide synthesis enzymes are encoded separately. Streptomyces coelicolor actinorhodin acyl carrier protein synthase (AcpS) IS a promiscuous enzyme involved in type II polyketide synthesis that catalyses the transfer of the phosphopantetheine chain from coenzyme A (CoA) to acyl carrier protein (ACP).
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:492473 |
| Date | January 2008 |
| Creators | Dall'Aglio, Patrick |
| Publisher | University of Bristol |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Source | http://hdl.handle.net/1983/22082f07-d6ef-47e1-ac8f-ba89ada01002 |
Page generated in 0.0017 seconds