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Replisome Dynamics ans Chromosome Segregation in Escherichia Coli

Replication of the chromosome of E. coli starts at a single point and proceeds bidirectionally until the replication forks meet at the opposite side of the DNA molecule. All this occurs on a compacted (around 1000-fold) chromosomal DNA, which is also organized in a manner that reflects the genetic position of the loci. Any roles that DNA replication plays in helping segregate the new DNA molecules, and how replication relates to nucleoid organization, remain to be understood.

Identiferoai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:490350
Date January 2008
CreatorsReyes, Rodrigo
PublisherUniversity of Oxford
Source SetsEthos UK
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation

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