Certain amino acids, notably L-glutamate and L-aspartate, are believed to fulfil a role as excitatory neurotransmitters in the mammalian Central Nervous System (CNS). Investigation has revealed the presence of three, and possibly a fourth, type of receptor for such neurotransmitters. These receptors have been named after the most potent and selective agonist of each; thus they are usually referred to as N-methyl-D-aspartate (A1), quisqualate (A2), kainate (A3) and 2-amino, 4-phosphono butyric acid (A4); the designations in brackets being that of the nomenclature of Fagg and Foster.
Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:372742 |
Date | January 1986 |
Creators | Badman, G. T. |
Publisher | London Metropolitan University |
Source Sets | Ethos UK |
Detected Language | English |
Type | Electronic Thesis or Dissertation |
Source | http://repository.londonmet.ac.uk/3278/ |
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