The motivation for the main body of work presented in this thesis arose from three sources. Initially, the need to develop and test a reliable, portable and unobtrusive method of observing human feeding behaviour in a clinical setting. Secondly, curiosity concerning the serotonergic modulation of feeding. In practice, to examine the effects of the 5-HT reuptake inhibitor and anti-depressant fluoxetine on food intake and choice, body weight and subjective states in both non-depressed normal-weight and obese subjects. The third and final impetus arose from the observation that, in rats, the expression of meal-induced satiety offered a background against which to examine the possible mechanisms underlying the effects of acute and chronic administration of serotonergic agents on consummatory and behavioural functioning.
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:317257 |
| Date | January 1992 |
| Creators | McGuirk, Joan Teresa |
| Publisher | London Metropolitan University |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Source | http://repository.londonmet.ac.uk/3393/ |
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