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Development of a mouse calvarial defect model for evaluation of biomaterials : an organ culture study

Mouse calvarial organ cultures have been widely utilized for investigating the biologic behaviour of intramembranous bones. This technique can be used to analyze bone both at the tissue and at the cellular level. It also has the ability to isolate local effects from systemic factors. The aim of this study was to establish a mouse calvarial critical size defect (CSD) model for evaluation of biomaterials in vitro.

Identiferoai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:506280
Date January 2009
CreatorsWu, Xiaohong
PublisherUniversity of Manchester
Source SetsEthos UK
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation

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