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Strategies for improving the biocompatabilitty and accuracy of additively photopolymerised micro-components

Projection-microstereolithography (PMSL) is an additive manufacturing technique based on the digitally supported and spatially controlled solidification of photopolymers and increasingly investigated as an enabling technique for novel applications in regenerative medicine. To better match the complex requirements defined by these emerging applications in terms of the biocompatibility of the fabricated components and their accuracy at micro scale, the process capabilities of this fabrication method need to be further extended. In this Ph.D. thesis, a methodology is proposed that comprises a set of novel experimental procedures and models to capture and predict the effects of essential but potentially toxic process additives such as photoinitiators and dyes on the output parameters of the process. Furthermore, a metrological concept is presented to assess the dimensional capabilities of this fabrication method by monitoring and predicting the level of accuracy in cylindrical micro-features that are highly relevant to biomedical applications.

Identiferoai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:606726
Date January 2013
CreatorsBail, Robert
PublisherUniversity of Nottingham
Source SetsEthos UK
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation

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