Erythropoiesis is the process in which a pluripotent stem cell differentiates into a mature red blood cell (RBC). Over the last two decades understanding of factors that regulate this process has increased, which has allowed for the development of advanced in vitro culture systems that can on a small scale, generate therapeutic quantities of mature RBCs from isolated stem cell populations. Not only does this create an alternative source of RBCs for use in medical treatments, it also provides a esearch model that can be used to investigate the underlying biochemical and physiological mechanisms of human erythropoiesis.
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:492444 |
| Date | January 2008 |
| Creators | Richardson, Ben Matthew |
| Publisher | University of Bristol |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
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