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Investigation of the interactions between breathing, beat by beat changes in RR intervals, and beat by beat changes in systolic pressure levels

Blood pressure is constantly changing due to internal and external influences. The body counteracts these changes via the baroreflex by altering heart rate, stroke volume and peripheral resistance. The integrity of the baroreflex is often measured by baroreflex sensitivity (BRS), the ratio of change in RR-interval to change in systolic pressure (SP). The simple model assumed by BRS is a black box, with an input, SP levels, and an output, RR-intervals, therefore BRS represents the gain of the system. If RR-intervals and SP levels are changing cyclically, for example in response to regular breathing, the phase offset between the input and output can also be measured.

Identiferoai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:493067
Date January 2008
CreatorsBowers, Emma Jane
PublisherUniversity of Newcastle Upon Tyne
Source SetsEthos UK
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation

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