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CaMK118 interaction with the RyR2 complex in normal and failing rabbit hearts

Cardiac Ca2+ cycling consist of a series of tightly controlled events, regulated by a number of key proteins that release and sequester Ca2+ both at the cell surface and via intracellular stores. RyR2 is the main SR Ca2+ release channel. Direct regulation of RyR2 by CaMKIId, an important Ca -dependent enzyme, has previously been demonstrated.

Identiferoai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:488532
Date January 2008
CreatorsAnthony, Diana Francesca
PublisherUniversity of Strathclyde
Source SetsEthos UK
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation

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