Stearoyl-CoA desaturase (SCD) catalyses the rate-limiting step in the biosynthesis of monounsaturated fatty acids by the insertion of a a ^9-cis double bond into acyl-CoA substrates in the presence of NADH and molecular oxygen. Recent work with animals in which expression of the enzyme has been eliminated, suggests a critical role for this enzyme in regulating lipid metabolism and obesity.
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:492395 |
| Date | January 2008 |
| Creators | Nair, Ajith Sreekantan |
| Publisher | Glasgow Caledonian University |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
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