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A computational analysis of the functional role of GABAergic synaptic transmission in striatal medium spiny neurons

Medium Spiny projection neurons, the sole output neurons of the striatum, are connected by GABAergic synapses. Such connections are classically assumed to be inhibitory, thus it has been suggested that one of the main functions of the striatum is to detect and classify cortical representations of sensory events to trigger appropriate motor responses through a winner-take-all network dynamic.

Identiferoai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:491856
Date January 2008
CreatorsAyling, Martin D. T.
PublisherUniversity of Manchester
Source SetsEthos UK
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation

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