Noxious stimuli have a profound influence on motor behaviour, but there is a paucity of information regarding how somatosensory information is transformed into a motor output. The cerebellum is the largest sensorimotor control structure within the brain and previous electrophysiological studies have demonstrated that climbing fibres, one of its major sources of afferent input, are activated in response to a noxious pinch stimulus. This thesis investigates the anatomical pathways by which nociceptive information may reach the cerebellum, with a particular focus upon the olivo-cerebellar system, the sole source of climbing fibres.
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:505762 |
| Date | January 2009 |
| Creators | Flavell, Charlotte Rachael |
| Publisher | University of Bristol |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
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