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Intermolecular interactions of general anaesthetics with cell membranes; effects on microdomains and the membrane dipole potential

General anaesthetic agents (GAs) have been used clinically for over a century, yet their mechanisms of actions remain a matter of debate. GAs affect a wide range of membrane lipid components but the actual molecular nature underlying the functional effect is yet to be explained. GAs are believed to alter the flow of sodium ions into neurons through the cell membrane. However, exactly how the anaesthetics achieve this is not yet fully understood.

Identiferoai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:490984
Date January 2008
CreatorsJamal, Ghadir A.
PublisherUniversity of Nottingham
Source SetsEthos UK
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation

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