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Neuroimaging of Cortical and Subcortical Respiratory Control Centres and their Modulation by Opioid analgesics

Opioids drugs are a mainstay for the treatment of acute and chronic pain, however their use is limited by potentially fatal depression of breathing. In this thesis we have set out to identify networks of respiratory control and to investigate the effects of the opioid drug remifentanil upon areas of the brain that control breathing, using functional magnetic resonance imaging (FMRI) in healthy human volunteers.

Identiferoai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:490345
Date January 2008
CreatorsPattinson, Kyle T. S.
PublisherUniversity of Oxford
Source SetsEthos UK
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation

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