Type-1 diabetes is caused by autoimmune destruction of insulin-producing β-cells in the pancreas. Today, transplantation of whole pancreas or islets is the only treatment that can restore endogenous insulin production. Within the past 20 years, pancreatic islet transplantation has become a clinical reality and an option in diabetes treatment. However, large use of this therapy is limited by shortage in organ donations and use of immunosuppressive drugs. Immunoisolation potentially allows elimination of immuosuppressive drugs and use of xenogenic tissue solving the problem of a shortage in organ donation.
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:494629 |
| Date | January 2009 |
| Creators | Cornolti, Roberta |
| Publisher | Open University |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
Page generated in 0.0021 seconds