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Epidemiology of renal failure : a population based study

Population based studies of early chronic kidney disease (CKD), acute renal failure (ARF) and acute on chronic renal failure (ACRF) are surprisingly sparse and bedevilled by differences in definition, which makes incidence, prevalence and particularly outcomes difficult to compare.  There are measures available to prevent progression of both ARF and CKD, emphasising the importance of early identification and referral for treatment.  The international Acute Dialysis Quality Initiative (ADQI) group have suggested a classification for ARF and ACRF.  Furthermore Kidney Dialysis Outcomes Quality Initiative (KDOQI) clinical practice guidelines have suggested a staging system for CKD based on severity.  In many countries it is difficult to obtain comprehensive, population based data because medical services are not linked to one population base.  The Grampian region has a population of 523,390 and only two hospitals with linked biochemistry laboratories and hence suitable for epidemiological studies.  I tested the hypotheses that incidence of ARF and ACRF is high and RIFLE classification predicts outcomes.  I also studied the epidemiology of CKD in this population by manually reviewing the case notes of the patients.

Identiferoai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:440595
Date January 2007
CreatorsAli, Tariq Zulfiqar
PublisherUniversity of Aberdeen
Source SetsEthos UK
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation

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