Growth factor receptor bound (Grb) protein 7 family and Proline-rich EVHl ligand (Prel) family proteins are adaptor proteins that share Pleckstrin homology (PH) and Ras-associating (RA) domain. Grb7 family members have been shown to play important roles in growth and signal transduction while members of the Prel family have been reported to function in cell adhesion and migration. Grb 10 interacting GYF domain (GIGYF) proteins were shown to interact with GrblO proline-rich moFif and have been implicated in familial Parkinson's Disease.
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:500712 |
| Date | January 2008 |
| Creators | Lee, Kuisoon |
| Publisher | University of Bath |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
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