Synchronised bursting of the basal ganglia, specifically at frequencies below 30 Hz, has been implicated to have a major role in the pathophysiology of Parkinson's disease (PD). The aim of this thesis is to further investigate the pathological role of low frequency activities in the subthalamic nucleus. These activities are characterised through exploration of their interactions with oscillatory cortical activities as well as with subthalamic prokinetic high frequency activities and by determining their contribution to parkinsonian bradykinesia.
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:420311 |
| Date | January 2005 |
| Creators | Fogelson, Noa |
| Publisher | University College London (University of London) |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Source | http://discovery.ucl.ac.uk/1445455/ |
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