Major depressive disorder is associated with dysfunctional motivation, reward and cognitive processing. A clinical feature of depression is low motivation but it remains unclear whether this reflects a fundamental impairment in basic incentive motivation or a higher level deficit in integrating cognitive and emotional information in complex situations. The focus of this thesis was to investigate the behavioural and neural bases underlying the processing of reward-related and motivational processes in major depression; in particular, the influence of variable reward magnitudes on incentive motivation and the interaction between information processing and response to reinforcement.
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:493459 |
| Date | January 2008 |
| Creators | Downey, Darragh |
| Publisher | University of Manchester |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
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