Sjogren's syndrome is a systemic autoimmune disorder which specifically targets the glands, primarily the salivary and lacrimal glands and leads to an impairment of secretory function and is characterised by lymphocytic infiltration of the salivary and lacrimal glands. Until relatively recently it was believed that the glandular function was a direct consequence of immune mediated destruction of the :inar tissue but most recent data suggests that the glandular hypofunction is more 5ly to be the result of immune mediated inhibition of acinar function, which if prolonged could lead to acinar atrophy.
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:501740 |
| Date | January 2008 |
| Creators | Caulfield, Vicky Louise |
| Publisher | University of Liverpool |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
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