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Splanchnic organ function and glucose metabolism during coronary artery bypass surgery with or without cardiopulmonary bypass

Methods: Patients were randomised to off-pump coronary artery bypass grafting (OPCAB) or conventional coronary artery bypass grafting with cardiopulmonary bypass (CABG-CPB). Small intestine function was assessed by differential four sugars (0=methyl-D-glucose, D-xylose, L-rhamnose, and Lactulose) permeability and absorption tests before surgery, at day 1 and day 5 post-surgery. Liver function was assessed before and at the end of surgery by monoethylglycinexyhdide (MEGX)/Iidocaine ratios after injection of 1 mg/kg bolus of lidocaine and by serial measurements of transaminases (AST and ALT), bilirubin, and alkaline phosphatase (ALP).

Identiferoai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:492604
Date January 2006
CreatorsRajakaruna, Chanaka
PublisherUniversity of Bristol
Source SetsEthos UK
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation

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