Pre-eclampsia (PE) is a pregnancy specific condition that affects 2-3% of women. At present the cause of PE is unknown, however the main pathological features are impaired placentation, with inadequate invasion of the spiral arteries by syncytiotrophoblasts, and systemic endothelial damage, contributing to increased perinatal and maternal morbidity and mortality. PE may have life time consequences for the fetus in terms of greater predisposition to adult cardiovascular disease.
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:491024 |
| Date | January 2008 |
| Creators | Mistry, Hiten |
| Publisher | University of Nottingham |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
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