Tc-99m-MIBI is a substrate for ATP-binding cassette (ABC) transporter proteins, including P-glycoprotein (P-gp), and has been used to image their expression, mainly in cancer. Imaging P-gp expression may have a role in renal transplantation and investigating drug toxicity. The aim of the project was to develop a functional imaging assay for ABC-transporters using Tc-99m-MIBI.
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:667853 |
| Date | January 2015 |
| Creators | Dizdarevic, Sabina |
| Publisher | University of Brighton |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Source | https://research.brighton.ac.uk/en/studentTheses/7b9f07b1-203b-468b-bea3-07168e1a24af |
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