Few studies have assessed the optimum second line highly active anti-retroviral therapy
(HAART) regimen in patients who had failed on the first-line HAART in resource-limited
settings. This study aimed to compare the Protease inhibitor (PI)-based second line
HAART regimens used in one clinic in Trinidad by comparing immunological, virological
and clinical outcomes of patients on the different second line HAART regimens.
The records of 35 treatment-experienced patients, over 21years of age and on PI-based
regimens for at least six months, were analysed using SPSS version 20.
The regimen containing TDF/FTC/AZT/LPV/r proved to produce superior outcomes
compared to the other second line regimens.
Due the small number of usable patients’ records, the findings cannot be generalised
but indicate directions for future studies attempting to compare the treatment outcomes
of different second line HAART regimens / Health Studies / M. A. (Public Health)
| Identifer | oai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:unisa/oai:uir.unisa.ac.za:10500/14199 |
| Date | 21 October 2014 |
| Creators | Ziregbe, Elohor |
| Contributors | Ehlers, V. J. |
| Source Sets | South African National ETD Portal |
| Language | English |
| Detected Language | English |
| Type | Dissertation |
| Format | 1 online resource (xiv, 90 leaves), application/pdf |
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