The aims of the research were to establish whether diphenylhydantoin and phenobarbitone are teratogenic in mice both in vivo and in an in vitro whole embryo culture system, to investigate possible mechanisms of teratogenicity and to examine whether the methods used in this study, may form a basis for developing systems of more extensive drug teratogenicity screening.
Identifer | oai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:uct/oai:localhost:11427/26474 |
Date | 04 August 2017 |
Creators | Beyers, Nulda |
Contributors | Folb, Peter I |
Publisher | University of Cape Town, Faculty of Health Sciences, Division of Clinical Pharmacology |
Source Sets | South African National ETD Portal |
Language | English |
Detected Language | English |
Type | Master Thesis, Masters, MSc |
Format | application/pdf |
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