<p dir="ltr">This thesis describes advancements in both chemical imaging and optical manipulation methodologies for their application in tandem monitoring and control of biochemical processes. We developed a fast acquisition multimodal nonlinear imaging platform based on pulse-picking to minimize photoperturbation to the sample during imaging. By frequency doubling the imaging source, through acousto-optic modulation and simple comparator circuitry, we developed a comprehensive platform that uses chemical specific signals generated during imaging to control the pixel location for laser activation for reaction control. This feedback loop allows for advanced decision logic on a pixel by pixel basis.</p>
| Identifer | oai:union.ndltd.org:purdue.edu/oai:figshare.com:article/25395811 |
| Date | 13 March 2024 |
| Creators | Matthew G Clark (18144661) |
| Source Sets | Purdue University |
| Detected Language | English |
| Type | Text, Thesis |
| Rights | CC BY 4.0 |
| Relation | https://figshare.com/articles/thesis/Innovations_for_improved_chemical_imaging_and_optical_manipulation_in_biological_systems/25395811 |
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