Article / Military personnel deployed to the Amazon Basin are at high risk for cutaneous leishmaniasis (CL). We responded
to an outbreak among Peruvian Army personnel returning from short-term training in the Amazon, conducting
active case detection, lesion sample collection, and risk factor assessment. The attack rate was 25% (76/303); the
incubation period was 2–36 weeks (median = 8). Most cases had one lesion (66%), primarily ulcerative (49%), and
in the legs (57%). Real-time polymerase chain reaction (PCR) identified Leishmania (Viannia) braziliensis (59/61 =
97%) and L. (V.) guyanensis (2/61 = 3%). Being male (risk ratio [RR] = 4.01; P = 0.034), not wearing long-sleeve
clothes (RR = 1.71; P = 0.005), and sleeping in open rooms (RR = 1.80; P = 0.009) were associated with CL.
Sodium stibogluconate therapy had a 41% cure rate, less than previously reported in Peru (70%; P < 0.001). After
emphasizing pre-deployment education and other basic prevention measures, trainees in the following year had
lower incidence (1/278 = 0.4%; P < 0.001). Basic prevention can reduce CL risk in deployed militaries.
| Identifer | oai:union.ndltd.org:PERUUPC/oai:repositorioacademico.upc.edu.pe:10757/558294 |
| Date | 20 June 2015 |
| Creators | Oré,Marianela, Sáenz, Eliana, Cabrera, Rufino, Sanchez, Juan F., De Los Santos, Maxy, Lucas, Carmen M., Núñez, Jorge, Edgel, Kimberly A., Sopan, Justino, Fernández, Jorge, Carnero, G, Andres M., Baldeviano, Christian, Arrasco, Juan C., Graf, Paul C. F., Lescano, Andres G. |
| Publisher | American Society of Tropical Medicine and Hygiene |
| Source Sets | Universidad Peruana de Ciencias Aplicadas (UPC) |
| Language | English |
| Detected Language | English |
| Type | info:eu-repo/semantics/article |
| Source | Universidad Peruana de Ciencias Aplicadas (UPC), Repositorio Académico - UPC |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | http://www.ajtmh.org/content/early/2015/06/11/ajtmh.15-0107.full.pdf+html |
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