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Poly(ADP-ribose) Synthesis as a Function of Growth and DNA Fragmentation

This work examines the synthesis of poly(ADP-ribose) in normal and SV40-transformed monolayer cultures of 3T3 cells as a function of growth and DNA fragmentation. A review of the relevant literature is given in the introduction of this work. Poly(ADP-ribose) synthesis has been implicated in transcription, replication, repair, differentiation and regulation of cell growth. The results of this study suggest that poly(ADP-ribose) synthesis is involved in some aspect of cell-growth control and DNA repair.

Identiferoai:union.ndltd.org:unt.edu/info:ark/67531/metadc332216
Date12 1900
CreatorsLevi, Viktorya
ContributorsJacobson, Myron, Gracy, Robert W., Schwartz, Martin, Harris, Ben G., Norton, S. J.
PublisherNorth Texas State University
Source SetsUniversity of North Texas
LanguageEnglish
Detected LanguageEnglish
TypeThesis or Dissertation
Formatv, 173 leaves : ill., Text
RightsPublic, Levi, Viktorya, Copyright, Copyright is held by the author, unless otherwise noted. All rights reserved.

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