Bacterial toxins have been shown to modify animal cell proteins in vivo with ADPR. Animal cells also contain endogenous enzymes that can modify proteins. Indirect evidence for the existence in vivo of rat liver proteins modified by ADPR on arginine residues has been reported previously. Presented here is direct evidence for the existence of ADP-ribosylarginine in rat liver proteins. Proteins were subjected to exhaustive protease digestion and ADP-ribosyl amino acids were isolated by boronate chromatography.
| Identifer | oai:union.ndltd.org:unt.edu/info:ark/67531/metadc277847 |
| Date | 05 1900 |
| Creators | Loflin, Paul T. (Paul Tracey) |
| Contributors | Jacobson, Myron, Norton, S. J., Masaracchia, Ruthann A., Benjamin, Robert C., Wu, Edward Ming-chi, 1938- |
| Publisher | University of North Texas |
| Source Sets | University of North Texas |
| Language | English |
| Detected Language | English |
| Type | Thesis or Dissertation |
| Format | xiii, 202 : ill., Text |
| Rights | Public, Copyright, Copyright is held by the author, unless otherwise noted. All rights reserved., Loflin, Paul T. (Paul Tracey) |
Page generated in 0.0055 seconds